MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis
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چکیده
منابع مشابه
MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis.
MICALs (molecules interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions. The molecular pathways employed by MICAL proteins to exert their cellular effects remain largely uncharacterized. Via an unbiased proteomics approach, we identify MICAL-1 as a binding partner of NDR (nuclear Dbf2-related) kinases. NDR1/2 kinases are known to mediate apoptosis downstre...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2011
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.01389-10